An H1 to relax chromatin?

نویسندگان

چکیده

برای دانلود رایگان متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

NAP1 modulates binding of linker histone H1 to chromatin and induces an extended chromatin fiber conformation.

NAP1 (nucleosome assembly protein 1) is a histone chaperone that has been described to bind predominantly to the histone H2A.H2B dimer in the cell during shuttling of histones into the nucleus, nucleosome assembly/remodeling, and transcription. Here it was examined how NAP1 interacts with chromatin fibers isolated from HeLa cells. NAP1 induced a reversible change toward an extended fiber confor...

متن کامل

Chromatin structure: Linking structure to function with histone H1

A recent study has determined the position and orientation in the nucleosome of the H1 variant 'linker histone' H5; the results focus attention on the unknown function of this highly abundant nuclear protein, and highlight the question of whether H1 is primarily an architectural or a gene-regulatory protein.

متن کامل

Histone H1 gets Pin’d onto chromatin

Histone H1 gets Pin'd onto chromatin T he proline isomerase Pin1 limits chromosome decon-densation by stabilizing a histone's association with chromatin, Raghuram et al. reveal. Histone H1 incorporates into nucleosomes to enhance chromatin folding and condensation. Phosphory-lation by the cyclin-dependent kinase Cdk2 promotes H1's dissociation from chromatin, perhaps by altering the conformatio...

متن کامل

Too busy to relax?

Today I am going to exercise. Finally! I plan to leave my offi ce early and go to the gym on my way home. I just need to complete a few telephone calls and I will be on my way. Suddenly, the emergency department calls. Mrs S. is back with congestive heart failure and will likely need admission. There goes my new resolution. By the time I leave the emergency department, it is time to go home, ha...

متن کامل

Room to Relax

Within a generation leisure time may loom as large in our lives a5 work does now. Michael Dower, director of the Dartington Amenity Research Trust, says that planning must start now if the space an^ facilities needed to enjoy leisure are going to be available. suppose you had a five-hour working day, a four-day weekend , a three-month annual holiday. How would you use your leisure? Within a gen...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: Journal of Cell Biology

سال: 2006

ISSN: 1540-8140,0021-9525

DOI: 10.1083/jcb.1756rr3